A risk factor is something that increases your chance of getting a disease or condition. Since Prader-Willi syndrome is caused by a random genetic defect, there are no known risk factors. However, in about 1% of cases, this defect may recur in the same family. Some genetic counselors recommend testing of affected children to identify very rare situations where the risk of recurrence might be 50%.
Lighter coloring compared with other family members
Diagnosis can be confirmed by genetic testing of a blood sample.
Treatment
Treatment, which continues into adulthood, is managed by the parents or caregivers of children with Prader-Willi syndrome. Key areas include:
Appetite and Weight
Perhaps the most important concern is managing food intake. People with Prader-Willi syndrome are unable to resist food. This is due to a defect in the part of the brain that controls the normal feelings of fullness when the body has had enough food. In addition, people with Prader-Willi syndrome have a slow metabolism. These traits can cause excessive weight gain, morbid obesity, and other related health problems. Research into the use of novel anti-obesity medications is underway.
Treatment:
Food restriction and supervision
Regular exercise
Behavior Issues
Infants and young children with Prader-Willi syndrome are typically happy and loving. But as they get older, you may notice behavior changes. Common behaviors include:
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
