Prostatectomy (Prostate Gland Removal)
(Prostate Gland Removal)
Click here to view an animated version of this procedure.
Definition
A prostatectomy is the surgical removal of an enlarged prostate gland. It is done to:
- Relieve urinary symptoms from a noncancerous condition (simple prostatectomy)
- Remove a prostate gland containing cancer (radical prostatectomy)
In some cases, some of the surrounding tissue is removed as well. Simple or radical prostatectomy can be done using open, laparoscopic, or robot-assisted surgery.
The prostate gland is part of a man's reproductive system. It makes and stores seminal fluid (a milky fluid that nourishes sperm and forms part of semen). The normal prostate is about the size of a walnut. It is located below the bladder and in front of the rectum.
Anatomy of the Prostate

© 2008 Nucleus Medical Art, Inc.
Reasons for Procedure
A prostatectomy is often done to treat these conditions:
Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is not related to prostate cancer development. It is relieved by transurethral resection or incision of the prostate (TURP or TUIP). Open surgery to remove the entire prostate is called a simple prostatectomy.
Prostate Cancer
Radical prostatectomy (complete removal of the prostate) is often considered in the early stages of prostate cancer, when it is confined to the prostate.
Risk Factors for Complications During the Procedure
- Obesity
- Chronic or recent illness
- Lung, kidney, or heart disease
- Excessive use of alcohol
- Smoking
- Use of narcotics or other mind-altering drugs
- Use of certain prescription medications, including muscle relaxants and sedatives, antihypertensives, insulin, beta-adrenergic blockers, and cortisone
- Diabetes
- Cirrhosis
What to Expect
Prior to Procedure
Your doctor will likely do the following:
- Physical exam
- Blood tests
- Urine tests
- Chest x-rays (for a simple prostatectomy)
- Kidney function tests
- Electrocardiogram (ECG, EKG)—a test that records the heart's activity by measuring electrical currents through the heart muscle
- Ultrasound (usually transrectal)—a test that uses sound waves to visualize the inside of the body
- Bone scan or CT scan if there is reason to suspect spread of cancer
In the days leading up to the procedure:
- Do not take aspirin, aspirin-containing products, or anti-inflammatory drugs (such as ibuprofen) for one week before the procedure.
- The night before, have a light meal and do not eat or drink anything after midnight.
Anesthesia
Usually general or spinal anesthesia is used.
Description of the Procedure
Transurethral Prostate Surgery
Transurethral resection of the prostate (TURP)—This uses a special instrument called a resectosope. It is inserted into the urethra through your penis. It is used to remove obstructing tissue from the inside of your gland. Newer procedures, such as laser surgery, have replaced the need for this procedure in some cases.
Transurethral incision of the prostate (TUIP)—This is similar to TURP, but prostate tissue is not removed. The surgeon makes 1-2 incisions where the prostate meets your bladder. This allows the urethra to expand and increase the flow of urine.
Simple Prostatectomy
Simple (open) prostatectomy—An incision is made in the lower abdomen to access the prostate. The inner part of your gland is removed. This procedure is not as common in the United States, and is considered when you have other complicating factors, such as stones or bladder damage.
Radical Prostatectomy
Radical retropubic prostatectomy—An incision is made in the lower abdomen between the navel and pubic bone. This allows the surgeon to access the prostate and pelvic lymph nodes. The prostate is detached from the bladder and urethra, and then the urethra is re-attached to the bladder. The surgeon will try to preserve nerve function related to bladder function and erections, if all the cancer can be removed safely. In some cases, the surgeon will remove lymph node tissue for testing before deciding to continue with the surgery. Depending on the number of cancerous lymph nodes, your age, and other factors, the surgeon will decide whether or not to proceed with the surgery.
Perineal radical prostatectomy—A half-moon incision is made between the anus and the scrotum. The prostate is then removed. This type of surgery is less common since it does not allow access to the lymph nodes. And it has a higher risk of nerve damage.
Both of these surgeries will require you to care for your catheter at home.
Robot-assisted laparoscopic radical prostatectomy (RALRP)—Five small “keyhole” incisions are made in the abdomen for robotic arms, including one with a small camera (laparoscope). This gives the surgeon a wider and more flexible range of motion. A surgeon sits at a console and guides the robotic arms through the surgery. Benefits include less scarring.
After Procedure
To reduce blood in the urine, water may be flushed through the bladder catheter that is inserted during surgery. This catheter will either be removed before you leave the hospital, or, in some cases, left in place for 1-3 weeks. This will allow for easier urination during the healing period. After a radical prostatectomy, many surgeons leave a JP® drain.
How Long Will It Take?
- TURP/TUIP: 1-1½ hours
- Simple prostatectomy: 2-4 hours
- Radical prostatectomy: 2-4 hours
Will It Hurt?
Anesthesia prevents pain during the procedure. You can expect some pain and discomfort for:
- 7-10 days after open surgery
- 3-4 days after laparoscopic surgery
Possible Complications
- Excessive bleeding
- Surgical wound infection
- Blood clots
- Inability to control urinary stream (incontinence)
- Fecal incontinence
- Impotence
- Retrograde ejaculation—Sperm ejaculates into your bladder, rather than out through the penis
- This may cause the urine to appear milky white after ejaculation.
- This would occur after TURP/TUIP. After open prostatectomy, patients are not able to ejaculate.
- Sterility
- Urethral stricture
- Low blood sodium after large amounts of fluid are used to irrigate the bladder during TURP/TUIP
- This can cause confusion, dizziness, high blood pressure, vomiting, and disturbed vision.
- Urine leak requiring prolonged drainage (with a catheter or drain) or reoperation
- Injury to the rectum or other adjacent structures
- This is a complication after radical prostatectomy only.
Average Hospital Stay
1-5 days
Postoperative Care
- Take medications as directed; you may be given antibiotics to prevent infection and/or stool softeners to prevent constipation.
- Do not take prescription pain medication for more than seven days. After this point, take non-prescription pain relievers (such as Advil or ibuprofen) as necessary, but avoid taking aspirin or aspirin-containing products.
- When resting in bed, keep legs elevated and moving to avoid deep vein blood clots.
- To promote healing, resume normal activities as quickly as possible.
- Drink plenty of liquids to clear your bladder of urine and blood.
- Shower as usual, but avoid baths until the surgical incision has completely healed.
- Wash the incision gently with mild soap and water.
- Do not drive for at least one month after surgery.
- Avoid vigorous exercise for six weeks after surgery.
- Resume sexual activity when able.
- Avoid coffee, tea, cola, cocoa, alcohol, spicy foods, or any other food or drink that might aggravate your stomach, intestines, bladder, or urinary tract.
Outcome
Complete healing from surgery usually occurs within six weeks.
You may need to take an antispasmodic medication for several weeks to normalize your bladder tone, but you can expect to regain normal urination function without dribbling.
You may be able to achieve an orgasm, but you may have no ejaculate or you may experience retrograde ejaculation.
If the cancer has spread from the prostate, other forms of treatment may be needed. These include radiation, chemotherapy, and hormone therapy.
Call Your Doctor If Any of the Following Occurs
- Signs of infection, including fever and chills
- Redness, swelling, increasing pain, excessive bleeding, or discharge from the incision site
- Cough, shortness of breath, chest pain, or severe nausea or vomiting
- Pain, burning, urgency, or frequency of urination, or persistent bleeding in the urine
- Bright red blood or blood clots in your urine
- Abdominal swelling or pain
- Headaches, muscle aches, dizziness, fever, or general ill feeling
- Constipation
- New, unexplained symptoms
- Poor urine drainage from catheter
RESOURCES:
Center for Prostate Disease Research
US Department of Defense
http://www.cpdr.org/
National Kidney and Urologic Diseases Information Clearinghouse
National Institutes of Health
http://kidney.niddk.nih.gov/
CANADIAN RESOURCES:
Canadian Prostate Cancer Network
http://www.cpcn.org/
Men's Health Centre
http://www.menshealthcentre.net/
The Prostate Centre
http://www.prostatecentre.ca/
Urology Resource Center Canada
http://urologyresourcecentre.org/
References:
Griffith HW, Moore S, Yoder K. Complete Guide to Symptoms, Illness & Surgery. New York, NY: Putnam Publishing Group; 2000.
Kaul S. Laparoscopic and robotic radical prostatectomy. eMedicine website. Available at: http://www.emedicine.com.
Le CQ, Gettman MT. Laparoscopic and robotic radical prostatectomy. Exper Rev Anticancer Ther. 2006;6:1003-1011.
Prostate cancer. Mayo Clinic website. Available at: http://www.mayoclinic.com/health/prostate-cancer/DS00043/DSECTION=8. Accessed May 5, 2008.
Prostate gland enlargement. Mayo Clinic website. Available at: http://www.mayoclinic.com/health/prostate-gland-enlargement/DS00027. Accessed May 5, 2008.
Prostate cancer treatment. National Cancer Institute website. Available at: cancer.gov/">http://www.cancer.gov/cancertopics/pdq/treatment/prostate/Patient/page4. Accessed June 17, 2008.
Last reviewed May 2008 by Adrienne Carmack, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © 2007 EBSCO Publishing All rights reserved.
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