Diabetes Insipidus Causes
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Causes of Diabetes Insipidus
ADH controls the amount of water reabsorbed by the kidneys. ADH is made in the

© 2009 Nucleus Medical Media, Inc.
- Central DI (up to 50% of cases, the cause is unknown) may be caused by:
- A lack of ADH made in the brain due to a genetic defect
- Damage to the hypothalamus or pituitary glands by surgery, infection, tumor, or head injury
- Sickle Cell Anemia
- NDI may be caused by:
- Renal cells in the kidneys not being able to conserve water, which may be due to a genetic defect in some cases
- Kidney diseases (such as Polycystic Kidney Disease )
- Medications (such as lithium , amphotericin B , or demeclocycline )-the most common cause of diabetes insipidus
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