Lesch-Nyhan Syndrome Causes
Learn what the medical community has uncovered about what causes Lesch-Nyhan Syndrome inside the condition center at ThirdAge.com. When you're done continue your research by selecting the next category in the left navigation.
Learn
- Overview
- What It Is
- Causes
- Risk Factors
- Diagnosis
- Symptoms
- Prognosis
- Living With
- Complications
- User Questions
Take Action
- Screening
- Medications
- Prevention
- Treatment
- Alternative Treatment
- Care Guide
- Questions for Your Doctor
- When to Contact a Doctor
- Find a Doctor
- Resource Guide
Causes of Lesch-Nyhan Syndrome
Lesch-Nyhan syndrome is caused by a mutation or change in a gene. This change results in the absence of the enzyme hypoxanthine-guanine phosphoribosyltransferase (HPRT). HPRT is needed to metabolize uric acid. Without this enzyme, uric acid builds up in the central nervous system, kidneys, and other areas of the body.
This gene mutation occurs on the X chromosome. It can either be a new mutation in the affected person or inherited from his mother, who is a carrier.
Latest Articles
There are no articles are available for Lesch-Nyhan Syndrome.
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor
implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A
MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment
or with any questions you may have regarding a medical condition. Copyright ©2013 EBSCO Publishing All rights
reserved. Source: EBSCO
