Persistent Pulmonary Hypertension Of The Newborn Causes

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Causes of Persistent Pulmonary Hypertension Of The Newborn


PPHN can be caused by a variety of factors, including:

  • An event or illness during pregnancy or childbirth
    • Meconium aspiration syndrome (the baby inhales the meconium-its first stool-prior to or shortly after birth)
    • Severe Pneumonia
    • Infection
    • Low blood sugar
    • Birth asphyxia (loss of oxygen to the fetus during delivery)
    • Respiratory Distress Syndrome In Newborns
    • Maternal use of nonsteroidal anti-inflammatory medications
    • Late trimester maternal use of selective serotonin reuptake inhibitors
    • Amniotic fluid leak
    • Low amniotic fluid (oligohydramnios)
    • Abnormal lung development as a result of congenital diaphragmatic hernia
  • Stress during pregnancy
  • Isolated condition with an unknown cause


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