Restless Legs Syndrome Causes

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Causes of Restless Legs Syndrome


The exact cause is unknown. RLS may occur for no identifiable reason. This is called primary RLS. Or, it may be caused by other conditions or certain drugs. This is called secondary RLS.

Many people with RLS also have periodic limb movement disorder (PLMD). This is a related motor disorder characterized by:

  • Involuntary, repetitive, jerking movements
  • Interrupted sleep because of movement


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