Common Questions About Arthritis |
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Dharma Singh Khalsa, M.D.
ThirdAge Pain Management Expert
Can You Rebuild Lost Cartilage?
Question: I've heard there is something that rebuilds the cartilage lost from arthritis, thus alleviating some pain. Is there any truth to this?
Answer: There are two compounds, glucosamine and chondroitin sulphate, effective at rebuilding lost cartilage. Glucosamine builds the water-holding molecules that keep cartilage slippery and strong. A reasonable dosage is 500 mg, three times a day. Chondroitin is a substance that attracts and holds water. Like glucosamine, it is extremely beneficial to the water tanks that keep cartilage strong and supple. A reasonable dosage of chondroitin can range from 1.5 to 3 grams daily, though there have been reports of people taking up to 10 grams per day without side effects.
SAMe, a form of amino acid called methionine, is another important anti-arthritis nutrient that stimulates production of two important components of cartilage. In one study of more than 20,000 arthritis patients, 80 percent of those taking SAMe experienced significant reductions of pain. A reasonable dose of SAMe is 1,000 mg per day.
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