Acid-Suppressing Meds Have Risks
A series of reports in the Archives of Internal Medicine note that proton pump inhibitors are associated with fractures in postmenopausal women as well as bacterial infections in many hospital patients. Researchers have also found that higher amounts of the drugs dont seem to be any more beneficial for treating ulcers than regular doses.
The study looking at the link between proton pump inhibitors and fractures, and conducted at the University of Washington, Seattle, involved over 160, 000 women between the ages of 50 and 79 (it was part of the Womens Health Initiative Study). The researchers followed the women for eight years and found that they had an increased risk of spine and forearm or wrist fractures, and simply more fractures overall.
Two studies looked at the association with bacterial infection, one at Beth Israel Deaconess Medical
Writing in an editorial that accompanied the journal reports, Mitchell H. Katz, M.D., of the San Francisco Department of Public Health, noted that between 53 and 69 percent of proton pump inhibitor prescriptions are prescribed inappropriately. That proton pump inhibitors relieve