New Drug Can Curb Dangerous Hepatitis

Effective Treatment For Hepatitis C

There’s good news for the 4.5 million Americans who have Hepatitis C. The Federal Drug Administration (FDA) recently announced that a new hepatitis C drug successfully treats the majority of patients with this disease.

Hepatitis C is one type of hepatitis --a liver disease - caused by the hepatitis C virus (HCV). It usually spreads through contact with infected blood. It can also spread through sex with an infected person and from mother to baby during childbirth. Most people who are infected with hepatitis C don't have any symptoms for years.

A blood test can tell if you have it. Usually, hepatitis C does not get better by itself. The infection can last a lifetime and may lead to scarring of the liver or liver cancer. Serious cases may need a liver transplant.  Hepatitis C is a major cause of liver transplants, and it kills about 12,000 U.S. patients a year, a number expected to triple by 2030 as baby boomers succumb to the disease.

The makers of the new drug, called Teleprevir, is Vertex. Another similar drug is also in the making by the pharmaceutical company Merck.  Both new drugs work by blocking the enzyme protease, which allows the hepatitis virus to reproduce. The new approach represents a breakthrough from older medicines, which are designed to help boost the immune system to fight hepatitis.

FDA scientists said 79 percent of first-time hepatitis C patients taking telaprevir and the older medicines were cured, compared to 46 percent of those taking the older medications alone, according to Vertex's studies. Among patients who had already been treated for hepatitis C once, 65 percent achieved a cure after taking telaprevir, compared with 17 percent of those taking the older medications. Like HIV drugs, the new drugs will be prescribed as part of a cocktail with the two older drugs to help lower viral levels. The current two-drug treatment for the virus cures only about 40 percent of people and causes side effects like nausea, fatigue and vomiting. The FDA noted that the drug is significantly less effective for African Americans and the most common side effects are a skin rash and fatigue. Robin Westen is ThirdAge’s medical reporter. Check for her daily updates. See what others have to say about this story or leave a comment of your own.
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