Takotsubo Cardiomyopathy: "Broken Heart Syndrome" More Common in Women

Takotsubo Cardiomyopathy, or “broken heart syndrome,” is more likely to be suffered by females.

Takotsubo Cardiomyopathy, or “broken heart syndrome,” is more likely to be suffered by females, when sudden or prolonged stress causes heart failure or heart attack-like symptoms.

Researchers found females are seven to nine times more likely to suffer from the ailment, which is usually triggered by events such as an emotional breakup or a death, reports AP.

In the first nationwide study of its kind, scientists discovered that patients usually recover with no permanent damage. However, in rare cases, it can prove fatal.

Dr. Mariell Jessup, a University of Pennsylvania heart failure specialist who has treated many such cases, said the typical case is "a woman who has just lost her husband,” AP reports.

The syndrome was first recognized around 1990 by Japanese doctors, who named it Takotsubo cardiomyopathy; tako tsubo are octopus traps that resemble the unusual pot-like shape of the stricken heart.

It occurs when a big shock, even a good one like a lottery win, triggers a rush of adrenaline and other stress hormones that cause the heart's main pumping chamber to balloon suddenly and not work right.

Tests show dramatic changes in rhythm and blood substances typical of a heart attack, but no artery blockages that typically cause one, reports AP.

Study leader Dr. Abhishek Deshmukh of the University of Arkansas, said, “I was very curious why only women were having this," prompting him to do the first large study of the problem. Using a federal database including about 1,000 hospitals, Deshmukh found a total of 6,229 cases in 2007. Only 671 involved men. After adjusting for high blood pressure, smoking and other factors that can affect heart problems, women appeared 7.5 times more likely to suffer the syndrome than men, AP reports. Women over 55 were three times more likely to suffer from the condition compared to younger women. Another finding was that women younger than 55 were 9.5 times more likely to suffer it than men of that age. Some experts believe that men are less at risk due to having more adrenaline receptors on cells in their hearts than women do, thus enabling them to handle stress better, reports AP. About 10 percent of victims will suffer a second episode sometime in their lives. And although heart attacks happen more in winter, broken heart syndrome is more common in summer. The study’s results were reported Wednesday at an American Heart Association conference in Florida, AP reports.
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