Alopecia (Hair Loss)

(Hair Loss)

by Debra Wood, RN [1]


Definition

Alopecia refers to hair [2] loss in areas of skin that normally have hair [2]. There are two forms of alopecia:

  • Scarring—This is the loss of hair [2] follicles, causing permanent hair [2] loss. Cutaneous lupus [3] erythematous and fungal kerions are the most prevalent forms of scarring alopecia.
  • Nonscarring—In this case, the hair [2] shaft is gone, but the follicles are still present. Because the hair [2] follicles still exist, it often is reversible. It can, however, develop into the scarring type. Alopecia areata is a type of non-scarring alopecia. It is an autoimmune process and the cause is not known. Hair loss lasts approximately six months.

Hair Loss

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Causes

Many things can cause alopecia, including:

  • Stress that prompts growing hairs to rest and shed
    • Illness or surgery
    • Prolonged fever
    • Childbirth
    • Emotional/psychological stress [4]
    • Crash dieting
  • Hormonal problems
    • Overactive or underactive thyroid gland
  • Medications
    • Blood thinners
    • Drugs for gout [5]
    • Chemotherapy [6] for cancer [7] treatment
    • Vitamin A
    • Birth control pills
    • Antidepressants
    • Blood pressure and heart [8] medications
  • Allergic reaction to medications
  • Radiation therapy [9]
  • Infections
    • Fungal infections [10]
    • Syphilis [11]
    • HIV [12]
    • Herpes simplex [13]
  • Autoimmune disorders
  • Systemic and discoid lupus erythematosus
  • Anemia [14]
  • Hair pulled too tightly by:
    • Hair rollers
    • Pigtails
    • Cornrows
  • Hot oil treatments (can inflame the hair [2] follicle and cause scarring)
  • Twisting and pulling hair [2] out due to psychiatric problems
  • Genes
    • Male-pattern baldness is usually inherited.
    • Birth defects can include problems with the hair [2] shaft.


Risk Factors

A risk factor is something that increases your chance of getting a disease or condition.

  • Family history of baldness or hair [2] loss
  • Advancing age (for male-pattern baldness only)
  • Pregnancy
  • Stress
  • Poor nutrition [15]


Symptoms

Alopecia symptoms depend on the type of hair [2] loss. Some of the more common symptoms include:

Male-pattern baldness:

  • Hair recedes
  • Hair falls out at the top of the head
  • Affects men and women

Female-pattern baldness:

  • Hair thins over the entire head
  • Hair comes out when brushing

Alopecia areata:

  • Rapid hair [2] loss
  • Round or oval patches of hair [2] loss
  • Sometimes tiny hairs are visible in the patches
  • Brittle and discolored fingernails and toenails with ridges

Stress-related:

  • Gradual shedding
  • Hairs come out with gentle pulling

Fungal infections:

  • Patches of hair [2] loss
  • Black dots in the patches
  • Itching
  • Scaling
  • Inflammation (such as redness)


Diagnosis

The doctor will ask about your symptoms and medical [16] history, and perform a physical exam. The doctor will examine the area(s) of hair [2] loss, noting the pattern of hair [2] loss and condition of the scalp.

This physical exam may include:

  • Gentle pulling on the hair [2]
  • Taking samples of scalp areas with inflammation and examining them under a microscope
  • Analyzing samples of hair [2]
  • Checking for hair [2] loss on other parts of the body

The doctor will ask questions about:

  • Diet
  • Hair care
  • Medication use
  • Your personal and family medical [16] history
  • Pregnancies, menopause [17], and monthly menstrual cycles

Other tests may include:

  • Blood tests to help identify underlying conditions that may be causing the hair [2] loss
  • Biopsy of the scalp—removal of a small tissue sample to be analyzed under the microscope


Treatment

Alopecia treatment depends on the cause of the condition. Treatments include:

Medications

  • Drugs to correct a hormonal imbalance or deficiency
  • Switching to a different medication if a drug you are taking is contributing to the hair [2] loss
  • Antifungal shampoos and pills to treat fungal infections
  • For baldness in men, a prescription drug taken in pill form (finasteride) Note: Pregnant women should not even handle this medication. Even a small amount absorbed through the skin of the hands can cause birth defects in baby boys.
  • Over-the-counter medication (minoxidil) that is applied to the scalp daily (must be used on a regular basis) Note: If you have heart [8] problems, discuss this drug with the doctor before using it.
  • To help speed-up hair [2] re-growth in alopecia areata, your doctor may inject a steroid preparation into your scalp.
  • For some patients, not responding to other therapies, topical immunotherapy (usually administered by a dermatologist) may be helpful. It involves applying an allergen to scalp that causes local reaction like redness, itching and also induces hair [2] growth.
  • Phototherapy [18] is another potential treatment for patients with alopecia areata. Therapy is usually administered for 4 to 6 months.

Lifestyle Changes

Be gentle with your hair [2]. Avoid pulling it tightly. If pulled over a long period of time, scarring can occur resulting in permanent hair [2] loss. If treatment does not correct the hair [2] loss, you may opt for a wig, hairpiece, or hair [2] weaving. If emotional stress [4] is the cause, learn and practice stress-management techniques.

Surgery

This can involve:

  • Hair transplant—taking hair [2] from the back and sides of the head and transplanting it in bald areas. As many as 300 grafts may be needed. You must return multiple times for the grafts.
  • Scalp reduction with flaps—cutting the scalp and pulling the areas with hair [2] closer together.

Chemotherapy Induced

  • It could be minimal, moderate or severe.
  • It is transient and completely reversible after discontinuation of chemotherapy.
  • Currently, there are no medications available that were shown to reduce the risk of alopecia associated with cancer [7] treatments.

Prevention

There are no prevention guidelines for the most common type of hair [2] loss, male-pattern baldness. However, the following tips may help you avoid other types of hair [2] loss:

  • Do not pull your hair [2] tightly into a ponytail, cornrows, or curlers.
  • Learn and practice stress-management techniques.
  • Obtain medical [16] care for acute illnesses and to manage chronic conditions.
  • Eat healthy, well-balanced meals.

RESOURCES:

American Academy of Dermatology
http://www.aad.org [19]

National Alopecia Areata Foundation
http://www.alopeciaareata.com [20]

CANADIAN RESOURCES:

BC Health Guide
http://www.bchealthguide.org/ [21]

Derm Web
http://www.dermatology.org/ [22]

References:

American Academy of Dermatology website. Available at: http://www.aad.org/default.htm [23] .

American Academy of Family Physicians website. Available at: http://www.aafp.org/online/en/home.html [24] .

Cecil Textbook of Medicine . 21st ed. WB Saunders Co;2000.

Dorr VJ. A practitioner's guide to cancer-related alopecia. Semin Oncol. 1998;25:562.

Griffith's 5-Minute Clinical Consult . Lippincott, Williams, and Wilkins;1999.

Harrison's Principles of Internal Medicine . The McGraw-Hill Co;1999.

Hussein, AM. Chemotherapy-induced alopecia: New developments. South Med J. 1993;86:489.

Mitchell, AJ, Douglass, MC. Topical photochemotherapy for alopecia areata. J Am Acad Dermatol. 1985; 12:644.

Price, VH. Treatment of hair [2] loss. N Engl J Med. 1999; 341:964.

Primary Care Medicine . 4th ed. Lippincott, Williams, and Wilkins;2000.

Taylor, CR, Hawk, JL. PUVA treatment of alopecia areata partialis, totalis and universalis: audit of 10 years' experience at St John's Institute of Dermatology. Br J Dermatol. 1995; 133:914.




Last reviewed November 2007 by Marcin Chwistek, MD [25]

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical [16] advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health [26] provider prior to starting any new treatment or with any questions you may have regarding a medical [16] condition.

Copyright © 2007 EBSCO Publishing All rights reserved.


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[3] http://www.thirdage.com/health-wellness/systemic-lupus-erythematosus-lupus-sle
[4] http://www.thirdage.com/stress
[5] http://www.thirdage.com/health-wellness/gout-gouty-arthritis
[6] http://www.thirdage.com/health-wellness/chemotherapy
[7] http://www.thirdage.com/living-with-cancer
[8] http://www.thirdage.com/heart-health
[9] http://www.thirdage.com/health-wellness/radiation-therapy-ionizing-radiation-radiotherapy-brachytherapy
[10] http://www.thirdage.com/encyclopedia/tinea-capitis-ringworm-of-the-scalp-fungal-infection-of-the-scalp
[11] http://www.thirdage.com/sexual-health/syphilis
[12] http://www.thirdage.com/asthma/acquired-immunodeficiency-syndrome-and-human-immunodeficiency-virus-aids-and-hiv
[13] http://www.thirdage.com/sexual-health/genital-herpes-herpes-simplex-virus-hsv—types-1-and-2
[14] http://www.thirdage.com/encyclopedia/disease-condition-injury-fact-sheets#a
[15] http://www.thirdage.com/nutrition
[16] http://www.thirdage.com/medical-care
[17] http://www.thirdage.com/menopause
[18] http://www.thirdage.com/encyclopedia/phototherapy
[19] http://www.aad.org
[20] http://www.alopeciaareata.com/
[21] http://www.bchealthguide.org/
[22] http://www.dermatology.org/
[23] http://www.aad.org/default.htm
[24] http://www.aafp.org/online/en/home.html
[25] http://www.thirdage.com/health-wellness/ebsco-publishings-medical-review-board-0#Chwistek
[26] http://www.thirdage.com/health-wellness